Organic changes in the brain in schizophrenia

Until now, schizophrenia is considered a functional psychosis, without any changes in the structure of the brain. But with the development of neuroimaging techniques, scientists began to find organic changes in the brain in schizophrenia. In schizophrenic patients, organic and functional changes were observed in regions responsible for motivational changes. And this is the ventral-tegmental region, the striatum in the region of the nucleus accumbens and the insular cortex. Changes were observed in the left s -ventralnyh front IC-connections. In the clinic of Doctor of Medical Sciences V.L. We briefly studied the encephalograms of patients with schizophrenia. Patients with auditory hallucinations were found to have bilaterally synchronous activity of the mediobasal structures. Delirium is accompanied by generalized dysrhythmia , which spreads to the frontal lobes of the brain. The catatonic form of schizophrenia is characterized by the activity of the mediobasal structures. In bipolar disorder, epileptiform activity is characteristic of the temporal lobe. Schizophrenia is also accompanied by asymmetric theta waveforms and short theta wave peaks and sharp peaks in the left hemisphere of the brain.

The study of the spectral profile of the electroencephalogram shows that in patients with schizophrenia, the activity of beta, theta, delta waves is greater than the activity of alpha waves. Children prone to developing schizophrenia have a similar EEG pattern. With the development of psychosis, deviations in the bioelectric activity of the brain are more pronounced. With a sluggish course of the disease on the EEG in combination with a neuronal test, there is a relationship between the mediators of glutamate and gamma aminobutyric acid and various networks of neurons. In schizophrenia, the number of gamkergic neurons in the cerebral cortex is reduced .

Thus, schizophrenia has an organic nature, so it is possible to influence the cause and cure the disease.

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